PLOS, the Public Library of Science, today announced the six finalists for the Accelerating Science Award Program (ASAP). The program recognizes the use of scientific research, published through open access, that has led to innovations benefiting society. Major sponsors include the Wellcome Trust and Google; ARL and SPARC are also among the program sponsors. Three top awards of $30,000 each will be announced on October 21 in Washington, DC, at an Open Access Week kick-off event hosted by SPARC and the World Bank. As award finalists, these individuals and teams are being honored for addressing a real-world challenge either by reusing previously published open access research or by creating a new repository of freely available research data to assist current and future collaborative research projects.